There are two major types of hormones produced by the adrenal gland , the mineralocorticoids and the glucocorticoids. This monograph discusses prednisone which is a synthetic glucocorticoid or corticosteroid. There are many different corticosteroid drugs available and different medical conditions are treated with different corticosteroid drugs based on the individual drug’s pharmacology (potency, speed of onset, duration of action). The other types of hormones produced by the adrenal gland are called mineralocorticoids. They primarily control salt and water balance in the body.
CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.
Long term use of topical corticosteroids can induce tachyphylaxis (tolerance to the vasoconstrictive action of topical corticosteroids). Adverse effects are uncommon when using mild to potent corticosteroids for less than three months, except when used on the face and neck, in intertriginous areas (skin folds), or under occlusion. However, very potent corticosteroids should not be used continuously for longer than three weeks. 2 If longer use of very potent corticosteroids is required, they should be gradually tapered to avoid rebound symptoms and then stopped for a period of at least one week after which treatment can be resumed. 2